Ancient Vicentine parish, it arose next to the bishop's castle - called the "Castellaro" - destroyed by Ezzelino da Romano around 1241 along with the one in Malo. The church is defined as a parish at the end of the 13th century.
The church of San Pietro Apostolo was the original church of Isola Vicentina. Built near the local castle (demolished by Ezzelino da Romano around 1241), it has been documented as a parish church since the 13th century. Thanks to the testimonies contained in two wills from the 15th century, it is known that at that time the church was a pieve and underwent some restorations.
The church was rebuilt several times: the first time between 1612 and 1613, the second was started in 1898 under the design and direction of architect Gerardo Marchioro di Domenico from Castelnovo. On October 15 of the same year, the solemn ceremony for laying the first stone took place.
On January 3 - at the death of Don Graziani - the choir, the nave up to the beginning of the side doors, and the oratory were covered. In 1906, Don Giovanni Battista Polacco took care of the construction of the sacristy above the land previously ceded by the Roi family.
By the end of 1912, the church was completely covered, and architect Marchioro dedicated himself to the work on the facade. In 1914, the facade itself was painted by the artist Attilio Bardin from Este, who also painted the choir, the oratory, and the sacristy. In December 1914, the church was opened for worship but without ceremony, as the Great War had meanwhile broken out.
In 1923, Gerardo's son, Domenico Marchioro, worked on the ceiling of the church, probably using his father's designs reproducing the cross-section for the construction of the ceiling.
